Download MendeleyCrystal Structure of pitrilysin, the prototype of insulin-degrading enzymes
Maskos, K., Jozic, D., Fernandez-Catalan, C.To be published.
1Q2L
Crystal Structure of pitrilysin
- PDB DOI: https://doi.org/10.2210/pdb1Q2L/pdb
- Classification: HYDROLASE
- Organism(s): Escherichia coli str. K-12 substr. W3110
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2003-07-25 Released: 2005-05-17
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.250
- R-Value Work: 0.210
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Protease III | 939 | Escherichia coli str. K-12 substr. W3110 | Mutation(s): 0 EC: 3.4.24.55 |  | |
UniProt | |||||
Find proteins for P05458 (Escherichia coli (strain K12)) Explore P05458 Go to UniProtKB: P05458 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P05458 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PT Query on PT | C [auth A] D [auth A] E [auth A] F [auth A] G [auth A] | PLATINUM (II) ION Pt HRGDZIGMBDGFTC-UHFFFAOYSA-N |  | ||
| ZN Query on ZN | B [auth A] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.250
- R-Value Work: 0.210
- Space Group: P 32 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 115.2 | α = 90 |
| b = 115.2 | β = 90 |
| c = 178.5 | γ = 120 |
| Software Name | Purpose |
|---|---|
| X-PLOR | refinement |
| SCALEPACK | data scaling |
| REFMAC | refinement |
| DENZO | data reduction |
Entry History
Deposition Data
- Released Date: 2005-05-17 Deposition Author(s): Maskos, K., Jozic, D., Fernandez-Catalan, C.
Revision History (Full details and data files)
- Version 1.0: 2005-05-17
Type: Initial release - Version 1.1: 2007-10-16
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Source and taxonomy, Version format compliance - Version 1.3: 2019-07-24
Changes: Advisory, Data collection, Refinement description - Version 1.4: 2024-02-14
Changes: Advisory, Data collection, Database references, Derived calculations
