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Crystal Structure of Fab 2G12 bound to Man1->2Man
1OP3
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Immune System
    Structure Weight: 94772.58
    Molecule: FAB 2G12, light chain
    Polymer: 1 Type: protein Length: 212
    Chains: K, L
    Fragment: light chain
    Organism: Homo sapiens
    Gene Name: IGKC
    UniProtKB: Protein Feature View | Search PDB | P01834  
    Molecule: FAB 2G12, heavy chain
    Polymer: 2 Type: protein Length: 225
    Chains: H, M
    Fragment: heavy chain
    Organism: Homo sapiens
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Cricetulus griseus  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Cricetulus griseus  
    Polymer: 3
    Scientific Name: Synthetic construct   Taxonomy    
     
  •   Related PDB Entries Hide
    Identifier Details
    1OM3  Crystal structure of Fab 2G12 unliganded 
    1OP5  Crystal structure of Fab 2G12 bound to Man9GlcNAc2 ligand 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    BEZ
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    BEZ C7 H6 O2
    BENZOIC ACID
    MAN
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    MAN C6 H12 O6
    ALPHA-D-MANNOSE
    MAN:1OP3
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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