1NEP
Crystal Structure Analysis of the Bovine NPC2 (Niemann-Pick C2) Protein
- PDB DOI: https://doi.org/10.2210/pdb1NEP/pdb
- Classification: LIPID BINDING PROTEIN
- Organism(s): Bos taurus
- Mutation(s): No
- Membrane Protein: Yes OPM
- Deposited: 2002-12-11 Released: 2003-01-28
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.70 Å
- R-Value Free: 0.212
- R-Value Work: 0.195
- R-Value Observed: 0.195
This is version 1.4 of the entry. See complete history.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Epididymal secretory protein E1 | 130 | Bos taurus | Mutation(s): 0 Membrane Entity: Yes |  | |
UniProt | |||||
Find proteins for P79345 (Bos taurus) Explore P79345 Go to UniProtKB: P79345 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P79345 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAG Query on NAG | B [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |  | ||
| PO4 Query on PO4 | C [auth A] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.70 Å
- R-Value Free: 0.212
- R-Value Work: 0.195
- R-Value Observed: 0.195
- Space Group: I 2 3
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 100.157 | α = 90 |
| b = 100.157 | β = 90 |
| c = 100.157 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| CNS | refinement |
| CNS | phasing |
Entry History
Deposition Data
- Released Date: 2003-01-28 Deposition Author(s): Friedland, N., Liou, H.-L., Lobel, P., Stock, A.M.
Revision History (Full details and data files)
- Version 1.0: 2003-01-28
Type: Initial release - Version 1.1: 2008-04-28
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Non-polymer description, Version format compliance - Version 1.3: 2011-11-16
Changes: Atomic model - Version 1.4: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Advisory, Data collection, Derived calculations, Structure summary
