Download MendeleyCatalytic and Structural Effects of Amino-Acid Substitution at His30 in Human Manganese Superoxide Dismutase
Borgstahl, G.E.O., Parge, H.E., Hickey, M.J., Beyer Jr., W.F., Hallewell, R.A., Tainer, J.A.To be published.
1N0N
Catalytic and Structural Effects of Amino-Acid Substitution at His30 in Human Manganese Superoxide Dismutase
- PDB DOI: https://doi.org/10.2210/pdb1N0N/pdb
- Entry: 1N0N supersedes: 1LUS
- Classification: OXIDOREDUCTASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2002-10-14 Released: 2002-11-06
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.82 Å
- R-Value Free: 0.241
- R-Value Work: 0.224
- R-Value Observed: 0.224
wwPDB Validation 3D Report Full Report
This is version 1.5 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Superoxide dismutase [Mn] | 199 | Homo sapiens | Mutation(s): 1 EC: 1.15.1.1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P04179 (Homo sapiens) Explore P04179 Go to UniProtKB: P04179 | |||||
PHAROS: P04179 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P04179 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | D [auth A], E [auth A], G [auth B], H [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| MN Query on MN | C [auth A], F [auth B] | MANGANESE (II) ION Mn WAEMQWOKJMHJLA-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.82 Å
- R-Value Free: 0.241
- R-Value Work: 0.224
- R-Value Observed: 0.224
- Space Group: P 61 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 79.815 | α = 90 |
| b = 79.815 | β = 90 |
| c = 240.882 | γ = 120 |
| Software Name | Purpose |
|---|---|
| MAR345 | data collection |
| SCALEPACK | data scaling |
| CNS | refinement |
| CNS | phasing |
Entry History
Deposition Data
- Released Date: 2002-11-06 Deposition Author(s): Borgstahl, G.E.O., Parge, H.E., Hickey, M.J., Beyer Jr., W.F., Hallewell, R.A., Tainer, J.A.
- This entry supersedes: 1LUS
Revision History (Full details and data files)
- Version 1.0: 2002-11-06
Type: Initial release - Version 1.1: 2008-04-28
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Derived calculations, Version format compliance - Version 1.3: 2017-10-11
Changes: Refinement description - Version 1.4: 2021-10-27
Changes: Database references, Derived calculations - Version 1.5: 2024-02-14
Changes: Data collection
