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Crystal structure of the D227A variant of Staphylococcal enterotoxin A in complex with human MHC class II
1LO5
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Immune System/toxin
    Structure Weight: 71830.22
    Molecule: HLA class II histocompatibility antigen, DR alpha chain
    Polymer: 1 Type: protein Length: 182
    Chains: A
    Fragment: extracellular domain
    Organism: Homo sapiens
    Gene Names: Gene View for HLA-DRA HLA-DRA1
    UniProtKB: Protein Feature View | Search PDB | P01903  
    Molecule: HLA class II histocompatibility antigen, DR-1 beta chain
    Polymer: 2 Type: protein Length: 190
    Chains: B
    Fragment: extracellular domain
    Organism: Homo sapiens
    Gene Name: Gene View for HLA-DRB1
    UniProtKB: Protein Feature View | Search PDB | P04229  
    Molecule: Hemagglutinin peptide
    Polymer: 3 Type: protein Length: 13
    Chains: C
    Molecule: enterotoxin A
    Polymer: 4 Type: protein Length: 233
    Chains: D
    Mutation: D227A
    Organism: Staphylococcus aureus
    Gene Name: entA
    UniProtKB: Protein Feature View | Search PDB | P0A0L2  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
    Polymer: 3
    Scientific Name: Synthetic construct   Taxonomy    
    Polymer: 4
    Scientific Name: Staphylococcus aureus   Taxonomy   Expression System: Escherichia coli  
     
  •   Related PDB Entries Hide
    Identifier Details
    1dlh  1DLH contains crystal structure of human MHC class II complexed with hemagglutinin peptide 
    1esf  1ESF contains crystal structure of Staphylococcal enterotoxin A 
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors
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