Crystal Structure of the anti-ErbB2 Fab2C4
1L7I
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Immune System
    Structure Weight: 47415.02
    Molecule: chimera of Fab2C4: "humanized" murine monoclonal antibody
    Polymer: 1 Type: protein Length: 214
    Chains: L
    Fragment: light chain (residues 1-214)
    Details: The chimera consists of the human Ig and the original murine sequence
    Organism: Homo sapiens
    UniProtKB: Protein Feature View | Search PDB | Q7Z3Y4  
    Molecule: chimera of Fab2C4: "humanized" murine monoclonal antibody
    Polymer: 2 Type: protein Length: 222
    Chains: H
    Fragment: heavy chain (residues 1-216)
    Details: The chimera consists of the human Ig and the original murine sequence
    Organism: Homo sapiens
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    SO4
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    SO4 O4 S
    SULFATE ION
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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