1ISJ
Crystal Structure Analysis of BST-1/CD157 complexed with NMN
- PDB DOI: https://doi.org/10.2210/pdb1ISJ/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens
- Expression System: Trichoplusia ni
- Mutation(s): Yes 
- Deposited: 2001-12-05 Released: 2002-03-13 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.241 
- R-Value Work: 0.215 
This is version 2.2 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
bone marrow stromal cell antigen 1 | 265 | Homo sapiens | Mutation(s): 3  EC: 3.2.2.5 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q10588 (Homo sapiens) Explore Q10588  Go to UniProtKB:  Q10588 | |||||
PHAROS:  Q10588 GTEx:  ENSG00000109743  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q10588 | ||||
Sequence AnnotationsExpand | |||||
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Oligosaccharides
Small Molecules
Ligands 1 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
NMN Query on NMN | E [auth A], F [auth B] | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE C11 H16 N2 O8 P DAYLJWODMCOQEW-TURQNECASA-O |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 Å
- R-Value Free: 0.241 
- R-Value Work: 0.215 
- Space Group: P 21 21 21
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 58.804 | α = 90 |
b = 112.59 | β = 90 |
c = 129.881 | γ = 90 |
Software Name | Purpose |
---|---|
MOSFLM | data reduction |
SCALA | data scaling |
CNS | refinement |
CCP4 | data scaling |
CNS | phasing |
Entry History 
Deposition Data
- Released Date: 2002-03-13  Deposition Author(s): Yamamoto-Katayama, S., Ariyoshi, M., Ishihara, K., Hirano, T., Jingami, H., Morikawa, K.
Revision History (Full details and data files)
- Version 1.0: 2002-03-13
Type: Initial release - Version 1.1: 2008-04-27
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Non-polymer description, Version format compliance - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Derived calculations, Structure summary - Version 2.1: 2021-11-10
Changes: Database references, Structure summary - Version 2.2: 2023-12-27
Changes: Data collection