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Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab.
1IQD
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Immune System/blood Clotting
    Structure Weight: 63403.60
    Molecule: HUMAN MONOCLONAL BO2C11 FAB LIGHT CHAIN
    Polymer: 1 Type: protein Length: 211
    Chains: A
    Organism: Homo sapiens
    Molecule: HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN
    Polymer: 2 Type: protein Length: 215
    Chains: B
    Organism: Homo sapiens
    Molecule: HUMAN FACTOR VIII
    Polymer: 3 Type: protein Length: 156
    Chains: C
    Fragment: C-TERMINAL DOMAIN
    Mutation: S2296C
    Organism: Homo sapiens
    Gene Names: Gene View for F8 F8C
    UniProtKB: Protein Feature View | Search PDB | P00451  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human  
    Polymer: 3
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Pichia pastoris  
     
  •   Related PDB Entries Hide
    Identifier Details
    1D7P  1D7P contains crystal structure of free factor VIII C2 domain. 
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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