Download MendeleyCrystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes
Mctigue, M.A., Davies II, J.F., Kaufman, B.T., Xuong, N.-H., Kraut, J.To be published.
1DR4
CRYSTAL STRUCTURES OF ORGANOMERCURIAL-ACTIVATED CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXES
- PDB DOI: https://doi.org/10.2210/pdb1DR4/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Gallus gallus
- Mutation(s): No
- Deposited: 1992-03-14 Released: 1993-10-31
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.40 Å
- R-Value Observed: 0.150
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| DIHYDROFOLATE REDUCTASE | 189 | Gallus gallus | Mutation(s): 0 EC: 1.5.1.3 |  | |
UniProt | |||||
Find proteins for P00378 (Gallus gallus) Explore P00378 Go to UniProtKB: P00378 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00378 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAP Query on NAP | D [auth A] | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE C21 H28 N7 O17 P3 XJLXINKUBYWONI-NNYOXOHSSA-N |  | ||
| HBI Query on HBI | E [auth A] | 7,8-DIHYDROBIOPTERIN C9 H13 N5 O3 FEMXZDUTFRTWPE-DZSWIPIPSA-N |  | ||
| HG Query on HG | B [auth A] | MERCURY (II) ION Hg BQPIGGFYSBELGY-UHFFFAOYSA-N |  | ||
| CA Query on CA | C [auth A] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.40 Å
- R-Value Observed: 0.150
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 89.08 | α = 90 |
| b = 48.29 | β = 124.8 |
| c = 64.32 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PROLSQ | refinement |
Entry History
Deposition Data
- Released Date: 1993-10-31 Deposition Author(s): Mctigue, M.A., Davies /II, J.F., Kaufman, B.T., Xuong, N.-H., Kraut, J.
Revision History (Full details and data files)
- Version 1.0: 1993-10-31
Type: Initial release - Version 1.1: 2008-03-24
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Derived calculations, Version format compliance - Version 1.3: 2017-11-29
Changes: Derived calculations, Other - Version 1.4: 2024-02-07
Changes: Data collection, Database references, Derived calculations
