CRYSTAL STRUCTURE OF THE HUMAN CLASS II MHC PROTEIN HLA-DR1 COMPLEXED WITH AN INFLUENZA VIRUS PEPTIDE
1DLH
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Histocompatibility Antigen
    Structure Weight: 90392.29
    Molecule: CLASS II HISTOCOMPATIBILITY ANTIGEN (HLA-DR1) (ALPHA CHAIN)
    Polymer: 1 Type: protein Length: 180
    Chains: A, D
    Organism: Homo sapiens
    Gene Names: Gene View for HLA-DRA HLA-DRA1
    UniProtKB: Protein Feature View | Search PDB | P01903  
    Molecule: CLASS II HISTOCOMPATIBILITY ANTIGEN (HLA-DR1) (BETA CHAIN)
    Polymer: 2 Type: protein Length: 188
    Chains: B, E
    Organism: Homo sapiens
    Gene Name: Gene View for HLA-DRB1
    UniProtKB: Protein Feature View | Search PDB | P04229  
    Molecule: ENTEROTOXIN TYPE B PRECURSOR
    Polymer: 3 Type: protein Length: 13
    Chains: C, F
    Organism: Influenza A virus (A/England/878/1969(H3N2))
    Gene Name: HA
    UniProtKB: Protein Feature View | Search PDB | P04664  
     
  •   Structure Validation Hide

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  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Spodoptera  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Spodoptera  
    Polymer: 3
    Scientific Name: Synthetic construct (Influenza A virus (A/England/878/1969(H3N2)))   Taxonomy    
    Polymer: 5
    Scientific Name: Synthetic construct   Taxonomy    
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    NAG
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    NAG C8 H15 N O6
    N-ACETYL-D-GLUCOSAMINE
    NDG
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    NDG C8 H15 N O6
    2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
    NDG:1DLH
     
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  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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  •   Deposition Summary Hide
    Authors:   Stern, L.J.

    Deposition:   1994-02-15
    Release:   1994-06-22
    Last Modified (REVDAT):   2011-07-13
     
  •   Revision History    Hide
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    2011-07-13
    Version format compliance
    2011-07-13
    Non-polymer description
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
    N/A
    Resolution[Å]:   2.80
    R-Value: 0.205 (obs.)
    R-Free: 0.304
    Space Group: P 43 21 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 94.60 α = 90.00 
    b = 94.60 β = 90.00 
    c = 247.50 γ = 90.00