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STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH 5'-DEOXY-5'-METHYLTHIOADENOSINE AND SULFATE AT 1.7 A RESOLUTION
1CG6
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Transferase
    Structure Weight: 31670.69
    Molecule: PROTEIN (5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE)
    Polymer: 1 Type: protein Length: 283
    Chains: A
    EC#: 2.4.2.28   
    Mutation: ILE56VAL
    Details: COMPLEXED WITH 5'-DEOXY-5'-METHYLTHIOADENOSINE AND SULFATE
    Organism: Homo sapiens
    Gene Names: Gene View for MTAP MSAP
    UniProtKB: Protein Feature View | Search PDB | Q13126  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli bl21(de3)  
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    MTA
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    MTA C11 H15 N5 O3 S
    5'-DEOXY-5'-METHYLTHIOADENOSINE
    MTA:1CG6
    SO4
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    SO4 O4 S
    SULFATE ION
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA,PQS (software)
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  •   Deposition Summary Hide
    Authors:   Appleby, T.C.,  Erion, M.D.,  Ealick, S.E.

    Deposition:   1999-03-27
    Release:   1999-07-05
    Last Modified (REVDAT):   2011-07-13
     
  •   Revision History    Hide
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    2011-07-13
    Version format compliance
    2011-07-13
    Biological assembly
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
    N/A
    Resolution[Å]:   1.70
    R-Value: 0.202 (work)
    R-Free: 0.225
    Space Group: P 3 2 1
    Unit Cell:
      Length [Å] Angles [°]
    a = 122.83 α = 90.00 
    b = 122.83 β = 90.00 
    c = 45.00 γ = 120.00