Structures of the psychrophilic Alteromonas haloplanctis alpha-amylase give insights into cold adaptation at a molecular level.
Aghajari, N., Feller, G., Gerday, C., Haser, R.(1998) Structure 6: 1503-1506
- PubMed: 9862804 
- DOI: https://doi.org/10.1016/s0969-2126(98)00149-x
- Primary Citation of Related Structures:  
1B0I - PubMed Abstract: 
. Enzymes from psychrophilic (cold-adapted) microorganisms operate at temperatures close to 0 degreesC, where the activity of their mesophilic and thermophilic counterparts is drastically reduced. It has generally been assumed that thermophily is associated with rigid proteins, whereas psychrophilic enzymes have a tendency to be more flexible.
Organizational Affiliation: 
Institut de Biologie et Chimie des Protéines UPR 412, CNRS 7 Passage du Vercors 69367 Lyon cedex 07 France.