Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin     DOI:10.2210/pdb1zyr/pdb

1ZYR Display Files close FASTA Sequence PDB File PDB File (Header) mmCIF File mmCIF File (Header) PDBML/XML File PDBML/XML File (Header) Download Files close FASTA Sequence PDB File (Text) PDB File (gz) mmCIF File mmCIF File (gz) PDBML/XML File PDBML/XML File (gz) Structure Factor (Text) Structure Factor (gz) Biological Assembly 1 (gz) (A+S) Biological Assembly 2 (gz) (A+S) Print this Page Share this Page close Email Delicious Stumble Google More... Link this Page

Primary Citation       Molecular Description Hide Classification: Transcription , Transferase Structure Weight: 854789.35   Molecule: DNA-directed RNA polymerase alpha chain Polymer: 1 Type: polypeptide(L) Length: 315 Chains: A, B, K, L EC#: 2.7.7.6    Fragment: subumit alpha Molecule: DNA-directed RNA polymerase beta chain Polymer: 2 Type: polypeptide(L) Length: 1119 Chains: C, M EC#: 2.7.7.6    Fragment: subunit beta Molecule: DNA-directed RNA polymerase subunit beta' chain Polymer: 3 Type: polypeptide(L) Length: 1524 Chains: D, N EC#: 2.7.7.6    Fragment: subunit beta-prime Molecule: DNA-directed RNA polymerase omega chain Polymer: 4 Type: polypeptide(L) Length: 99 Chains: E, O Fragment: subunit omega Molecule: DNA-directed RNA polymerase sigma chain Polymer: 5 Type: polypeptide(L) Length: 423 Chains: F, P Fragment: subunit sigma       Source Hide Polymer: 1 Scientific Name: Thermus thermophilus   Polymer: 2 Scientific Name: Thermus thermophilus   Polymer: 3 Scientific Name: Thermus thermophilus   Polymer: 4 Scientific Name: Thermus thermophilus   Polymer: 5 Scientific Name: Thermus thermophilus         Related PDB Entries Hide Id Details 1I6H  RNA Polymerase II Elongation Complex  1IW7  Structural Basis For Transcription Regulation By Alarmone Ppgpp  1K83  Crystal Structure Of Yeast RNA Polymerase II Complexed With The Inhibitor alpha-Amanitin  1SMY  Crystal Structure Of The RNA Polymerase Holoenzyme From Thermus Thermophilus At 2.6A Resolution  1YNJ  Taq RNA Polymerase-Sorangicin Complex  1YNN  Taq RNA Polymerase-Rifampicin Complex        Ligand Chemical Component Hide Identifier Name Formula Interaction View Links MG     MAGNESIUM ION Mg Ligand Explorer STD     STREPTOLYDIGIN C32 H44 N2 O9 Ligand Explorer ZN     ZINC ION Zn Ligand Explorer       Derived Data Hide SCOP Classification v1.75 - (20 Domains) CATH Classification v3.2.0 - (24 Domains) PFAM Classification - (38 Domains) GO Terms - (34 Terms)     Reset Layout

Biological Assembly 1     More Images... View in Jmol Other Viewers close KiNG WebMol QuickPDB FirstGlance Kiosk SimpleViewer Protein Workshop Ligand Explorer Biological assembly 1 assigned by authors and generated by PISA (software) Biological assembly 2 assigned by authors and generated by PISA (software)         Deposition Summary Hide Authors:   Tuske, S.,   Sarafianos, S.G.,   Wang, X.,   Hudson, B.,   Sineva, E.,   Mukhopadhyay, J.,   Birktoft, J.J.,   Leroy, O.,   Ismail, S.,   Clark, A.D.,   Dharia, C.,   Napoli, A.,   Laptenko, O.,   Lee, J.,   Borukhov, S.,   Ebright, R.H.,   Arnold, E. Deposition:   2005-06-10 Release:   2005-09-13 Last Modified (REVDAT):   2009-02-24       Experimental Details Hide Method:   X-RAY DIFFRACTION Experimental Data:   Resolution[Å]: 3.00 R-Value: 0.261 (work) R-Free: 0.282 Space Group: P 32 Unit Cell:   Length [Å] Angles [°] a = 237.00 α = 90.00  b = 237.00 β = 90.00  c = 250.00 γ = 120.00        Structure Links Hide Molecule of the Month Features: Catabolite Activator Protein