Human Adenine Phosphoribosyltransferase in Apo and AMP Complexed Forms
1ZN9
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Transferase
    Structure Weight: 39607.02
    Molecule: Adenine phosphoribosyltransferase
    Polymer: 1 Type: protein Length: 180
    Chains: A, B
    EC#: 2.4.2.7   
    Organism: Homo sapiens
    Gene Name: Gene View for APRT
    UniProtKB: Protein Feature View | Search PDB | P07741  
     
  •   Structure Validation Hide

    View the full validation report  

     

  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli bl21(de3)  
     
  •   Related PDB Entries Hide
    Identifier Details
    1ORE   Structure of human adenine phosphoribosyltransferase 
    1ZN7   Same protein complexed with PRPP, ADE and R5P 
    1ZN8   Same protein complexed with AMP, in space group P1 at 1.76 A resolution 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    AMP
    Search 
    Download 
    AMP C10 H14 N5 O7 P
    ADENOSINE MONOPHOSPHATE
    AMP:1ZN9
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors
Downloadable viewers:
 
 
 
  •   MyPDB Personal Annotations Hide
     
  •   Deposition Summary Hide
    Authors:   Iulek, J.,  Silva, M.,  Tomich, C.H.T.P.,  Thiemann, O.H.

    Deposition:   2005-05-11
    Release:   2006-04-25
    Last Modified (REVDAT):   2011-07-13
     
  •   Revision History    Hide
    Mouse over text for details
    2011-07-13
    Version format compliance
    2011-07-13
    Flag residual B-value
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   2.05
    R-Value: 0.154 (obs.)
    R-Free: 0.225
    Space Group: P 21 21 21
    Unit Cell:
      Length [Å] Angles [°]
    a = 47.51 α = 90.00 
    b = 49.25 β = 90.00 
    c = 140.10 γ = 90.00