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Human Adenine Phosphoribosyltransferase Complexed with AMP, in Space Group P1 at 1.76 A Resolution
1ZN8
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Transferase
    Structure Weight: 39989.70
    Molecule: Adenine phosphoribosyltransferase
    Polymer: 1 Type: protein Length: 180
    Chains: A, B
    EC#: 2.4.2.7   
    Organism: Homo sapiens
    Gene Name: Gene View for APRT
    UniProtKB: Protein Feature View | Search PDB | P07741  
     
  •   Structure Validation Hide

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  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli bl21(de3)  
     
  •   Related PDB Entries Hide
    Identifier Details
    1ORE  Structure of human adenine phosphoribosyltransferase 
    1ZN7  Same protein complexed with PRPP, ADE and R5P 
    1ZN9  Same protein in Apo and AMP Complexed Forms 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    AMP
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    AMP C10 H14 N5 O7 P
    ADENOSINE MONOPHOSPHATE
    AMP:1ZN8
    CL
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    CL Cl
    CHLORIDE ION
     
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Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors
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  •   Deposition Summary Hide
    Authors:   Iulek, J.,  Silva, M.,  Tomich, C.H.T.P.,  Thiemann, O.H.

    Deposition:   2005-05-11
    Release:   2006-04-25
    Last Modified (REVDAT):   2011-07-13
     
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    2011-07-13
    Version format compliance
    2011-07-13
    Flag residual B-value
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   1.76
    R-Value: 0.160 (obs.)
    R-Free: 0.211
    Space Group: P 1
    Unit Cell:
      Length [Å] Angles [°]
    a = 47.06 α = 75.41 
    b = 47.47 β = 68.42 
    c = 47.84 γ = 61.49