Crystal structure of isoflavanone 4'-O-methyltransferase complexed with (+)-6a-hydroxymaackiain
1ZGA
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Plant Protein , Transferase
    Structure Weight: 40780.78
    Molecule: Isoflavanone 4'-O-methyltransferase'
    Polymer: 1 Type: protein Length: 357
    Chains: A
    EC#: 2.1.1.212    2.1.1.46   
    Organism: Medicago truncatula
    Gene Name: HI4'OMT
    UniProtKB: Protein Feature View | Search PDB | Q29U70  
     
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  •   Source Hide
    Polymer: 1
    Scientific Name: Medicago truncatula   Taxonomy   Common Name: Barrel medic Expression System: Escherichia coli bl21  
     
  •   Related PDB Entries Hide
    Identifier Details
    1ZG3   Crystal structure of the same protein complexed with 2,7,4'-trihydroxyisoflavanone 
    1ZGJ   Crystal structure of the same protein complexed with (+)-pisatin 
    1ZHF   Crystal structure of Slelenomethionine substituted isoflavanone 4'-O-methyltransferase 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    HMK
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    HMK C16 H12 O6
    (6AR,12AR)-6H-[1,3]DIOXOLO[5,6][1]BENZOFURO[3,2- C]CHROMENE-3,6A(12AH)-DIOL
    HMK:1ZGA
    SAH
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    SAH C14 H20 N6 O5 S
    S-ADENOSYL-L-HOMOCYSTEINE
    SAH:1ZGA
     
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Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA,PQS (software)
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  •   Deposition Summary Hide
    Authors:   Liu, C.-J.,  Deavours, B.E.,  Richard, S.,  Ferrer, J.-L.,  Dixon, R.A.,  Noel, J.P.

    Deposition:   2005-04-20
    Release:   2006-08-01
    Last Modified (REVDAT):   2014-11-12
     
  •   Revision History    Hide
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    2014-11-12
    Function and keywords
    2011-07-13
    Biological assembly
    2011-07-13
    Version format compliance
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   2.35
    R-Value: 0.209 (obs.)
    R-Free: 0.247
    Space Group: P 43 2 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 71.22 α = 90.00 
    b = 71.22 β = 90.00 
    c = 188.91 γ = 90.00