the Plasmodium falciparum Cysteine Protease Falcipain-2
1YVB
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Hydrolase/hydrolase Inhibitor
    Structure Weight: 39867.39
    Molecule: falcipain 2
    Polymer: 1 Type: protein Length: 241
    Chains: A
    EC#: 3.4.22   
    Organism: Plasmodium falciparum 3D7
    UniProtKB: Protein Feature View | Search PDB | Q9N6S8  
    Molecule: Cystatin
    Polymer: 2 Type: protein Length: 111
    Chains: I
    Organism: Gallus gallus
    UniProtKB: Protein Feature View | Search PDB | P01038  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Plasmodium falciparum   Taxonomy   Expression System: Escherichia coli  
    Polymer: 2
    Scientific Name: Gallus gallus   Taxonomy   Common Name: Chicken  
     
  •   Related PDB Entries Hide
    Identifier Details
    1AIM   cruzain 
    1ATK   human cathepsin K 
    1PE6   papain 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    GOL
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    GOL C3 H8 O3
    GLYCEROL
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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  •   Deposition Summary Hide
    Authors:   Wang, S.X.

    Deposition:   2005-02-15
    Release:   2006-03-28
    Last Modified (REVDAT):   2011-07-13
     
  •   Revision History    Hide
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    2011-07-13
    Version format compliance
    2011-07-13
    Source and taxonomy
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   2.70
    R-Value: 0.232 (obs.)
    R-Free: 0.264
    Space Group: P 43 21 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 96.04 α = 90.00 
    b = 96.04 β = 90.00 
    c = 124.16 γ = 90.00