MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF P53
1YCR
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Complex (oncogene Protein/peptide)
    Structure Weight: 14343.49
    Molecule: MDM2
    Polymer: 1 Type: protein Length: 109
    Chains: A
    EC#: 6.3.2   
    Fragment: RESIDUES 17 - 125
    Organism: Homo sapiens
    Gene Name: Gene View for MDM2
    UniProtKB: Protein Feature View | Search PDB | Q00987  
    Molecule: P53
    Polymer: 2 Type: protein Length: 15
    Chains: B
    Fragment: RESIDUES 15 - 29
    Organism: Homo sapiens
    Gene Names: Gene View for TP53 P53
    UniProtKB: Protein Feature View | Search PDB | P04637  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
    Polymer: 2
    Scientific Name: Synthetic construct (Homo sapiens)   Taxonomy    
     
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  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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  •   Deposition Summary Hide
    Authors:   Kussie, P.H.,  Pavletich, N.P.

    Deposition:   1996-09-30
    Release:   1997-11-19
    Last Modified (REVDAT):   2009-02-24
     
  •   Revision History    Hide
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    2011-07-13
    Version format compliance
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
    N/A
    Resolution[Å]:   2.60
    R-Value: 0.200 (obs.)
    R-Free: 0.276
    Space Group: C 2 2 21
    Unit Cell:
      Length [Å] Angles [°]
    a = 43.41 α = 90.00 
    b = 100.55 β = 90.00 
    c = 54.85 γ = 90.00