1XOG
N9 Tern Influenza neuraminidase complexed with a 2,5-Disubstituted tetrahydrofuran-5-carboxylic acid
- PDB DOI: https://doi.org/10.2210/pdb1XOG/pdb
- Classification: HYDROLASE
- Organism(s): Influenza A virus
- Mutation(s): No 
- Deposited: 2004-10-06 Released: 2005-01-11 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.80 Å
- R-Value Free: 0.297 
- R-Value Work: 0.221 
wwPDB Validation   3D Report Full Report
This is version 2.0 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Neuraminidase | 387 | Influenza A virus | Mutation(s): 0  EC: 3.2.1.18 | ||
UniProt | |||||
Find proteins for P03472 (Influenza A virus (strain A/Tern/Australia/G70C/1975 H11N9)) Explore P03472  Go to UniProtKB:  P03472 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P03472 | ||||
Sequence AnnotationsExpand | |||||
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Oligosaccharides
Entity ID: 2 | |||||
---|---|---|---|---|---|
Molecule | Chains | Length | 2D Diagram | Glycosylation | 3D Interactions |
alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | B | 6 | N/A | ||
Glycosylation Resources | |||||
GlyTouCan:  G01760ZU GlyCosmos:  G01760ZU GlyGen:  G01760ZU |
Small Molecules
Ligands 3 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
ABW Query on ABW | F [auth A] | 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-2,5-ANHYDRO-3,4-DIDEOXY-4-(METHOXYCARBONYL)PENTONIC ACID C14 H23 N O6 MUJPWSPVNZGJOW-WRWGMCAJSA-N | |||
NAG Query on NAG | D [auth A], E [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N | |||
MAN Query on MAN | C [auth A] | alpha-D-mannopyranose C6 H12 O6 WQZGKKKJIJFFOK-PQMKYFCFSA-N |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.80 Å
- R-Value Free: 0.297 
- R-Value Work: 0.221 
- Space Group: I 4 3 2
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 180.344 | α = 90 |
b = 180.344 | β = 90 |
c = 180.344 | γ = 90 |
Software Name | Purpose |
---|---|
CNX | refinement |
HKL-2000 | data reduction |
SCALEPACK | data scaling |
CNS | phasing |
Entry History 
Deposition Data
- Released Date: 2005-01-11  Deposition Author(s): Wang, G.T., Wang, S., Gentles, R., Sowin, T., Maring, C.J., Kempf, D.J., Kati, W.M., Stoll, V., Stewart, K.D., Laver, G.
Revision History (Full details and data files)
- Version 1.0: 2005-01-11
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Non-polymer description, Version format compliance - Version 1.3: 2020-02-12
Changes: Advisory, Data collection, Derived calculations - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Advisory, Atomic model, Data collection, Derived calculations, Structure summary