Download MendeleyNMR structure of growth factor receptor binding protein SH2 domain complexed with the inhibitor
Ogura, K., Shiga, T., Yuzawa, S., Yokochi, M., Burke, T.R., Inagaki, F.To be published.
1X0N
NMR structure of growth factor receptor binding protein SH2 domain complexed with the inhibitor
- PDB DOI: https://doi.org/10.2210/pdb1X0N/pdb
- Classification: PEPTIDE BINDING PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2005-03-24 Released: 2005-04-19
Experimental Data Snapshot
- Method: SOLUTION NMR
- Conformers Calculated: 100
- Conformers Submitted: 20
- Selection Criteria: structures with the lowest energy
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Growth factor receptor-bound protein 2 | 104 | Homo sapiens | Mutation(s): 0 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P62993 (Homo sapiens) Explore P62993 Go to UniProtKB: P62993 | |||||
PHAROS: P62993 GTEx: ENSG00000177885 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P62993 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| DTF Query on DTF | B [auth A] | 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID C37 H45 N4 O7 P RHYFMOCFCFUTNH-GZNVFMSSSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: SOLUTION NMR
- Conformers Calculated: 100
- Conformers Submitted: 20
- Selection Criteria: structures with the lowest energy
Entry History
Deposition Data
- Released Date: 2005-04-19 Deposition Author(s): Ogura, K., Shiga, T., Yuzawa, S., Yokochi, M., Burke, T.R., Inagaki, F.
Revision History (Full details and data files)
- Version 1.0: 2005-04-19
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2022-03-02
Changes: Data collection, Database references, Derived calculations
