Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target
Primary Citation
  •   Molecular Description Hide
    Classification: Hydrolase
    Structure Weight: 21525.38
    Molecule: protease
    Polymer: 1 Type: protein Length: 99
    Chains: A, B
    Mutation: L10I, D25N, M36V, M46L, I54V, I62V, L63P, A71V, V82A, I84V, L90M
    Organism: Human immunodeficiency virus 1
    Gene Name: pol
    UniProtKB: Protein Feature View | Search PDB | Q5RTL1  
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot

  •   Related Citations in PDB Entry (REMARK 1) Hide
  •   Source Hide
  •   Related PDB Entries Hide
    Identifier Details
    1RPI   MDR 769 uncomplexed 
    1RQ9   MDR 769 complexed with DMP450 (mozenavir) 
    1RV7   MDR 769 complexed with lopinavir 
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    NA Na
  •   External Domain Annotations Hide
  •   Structural Biology Knowledgebase Data Hide
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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