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CRYSTAL STRUCTURE OF DECAMER NCP1 SUBSTRATE PEPTIDE IN COMPLEX WITH WILD-TYPE D25N HIV-1 PROTEASE VARIANT
 
 
DOI:10.2210/pdb1tsu/pdb
1TSU
 
Primary Citation
spinning wheel
 
 
  •  
    Move Section Molecular Description Hide
    Classification: Viral Protein/hydrolase
    Structure Weight: 22536.89
     
    Molecule:Pol polyprotein
    Polymer:1Type:polypeptide(L)Length:99
    Chains:A, B
    EC#:3.4.23.16 Go to IUBMB EC entry  
    Fragment:Protease
    Mutation:Q7K,D25N,L63P
    Molecule:NC-P1 SUBSTRATE PEPTIDE
    Polymer:2Type:polypeptide(L)Length:8
    Chains:P
     
     
  •  
    Move Section Source Hide
    Polymer: 1
    Scientific Name: Synthetic construct Go to NCBI Taxonomy entry  
    Polymer: 2
    Scientific Name: Synthetic construct Go to NCBI Taxonomy entry  
     
     
  •  
    Move Section Derived Data Hide
     
     
 
< Biological Assembly    Help
 
 
 
  •  
    Move Section Deposition Summary Hide
    Authors:   Prabu-Jeyabalan, M.,   Nalivaika, E.A.,   King, N.M.,   Schiffer, C.A.

    Deposition:   2004-06-21
    Release:   2005-03-29
    Last Modified (REVDAT):   2009-02-24
     
     
  •  
    Move Section Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Experimental Data:   N/A
    View a histogram of Resolution Resolution[Å]: 2.10
    R-Value: 0.207 (obs.)
    R-Free: 0.234
    Space Group: P 21 21 21
    Unit Cell:
      Length [Å] Angles [°]
    a = 51.06 α = 90.00 
    b = 57.73 β = 90.00 
    c = 61.49 γ = 90.00