Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
1TQ6
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Signaling Protein
    Structure Weight: 48117.40
    Molecule: interferon-inducible GTPase
    Polymer: 1 Type: protein Length: 413
    Chains: A
    EC#: 3.6.5   
    Mutation: M173A
    Organism: Mus musculus
    Gene Names: Iigp1 Irga6
    UniProtKB: Protein Feature View | Search PDB | Q9QZ85  
     
  •   Structure Validation Hide

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  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Mus musculus   Taxonomy   Common Name: House mouse Expression System: Escherichia coli bl21(de3)  
     
  •   Related PDB Entries Hide
    Identifier Details
    1DG3    
    1F5N    
    1TPZ   the same protein with GDP 
    1TQ2   the same protein with GNP 
    1TQ4   the same protein, K48A mutant with GDP 
    1TQD   The same protein without nucleotide 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    GNP
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    GNP C10 H17 N6 O13 P3
    PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
    GNP:1TQ6
    MG
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    MG Mg
    MAGNESIUM ION
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors
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  •   Deposition Summary Hide
    Authors:   Ghosh, A.,  Uthaiah, R.,  Howard, J.,  Herrmann, C.,  Wolf, E.

    Deposition:   2004-06-16
    Release:   2004-09-21
    Last Modified (REVDAT):   2009-02-24
     
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    2011-07-13
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  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   2.70
    R-Value: 0.238 (obs.)
    R-Free: 0.273
    Space Group: P 21 21 21
    Unit Cell:
      Length [Å] Angles [°]
    a = 71.04 α = 90.00 
    b = 74.46 β = 90.00 
    c = 91.39 γ = 90.00