Core domain of HIV-1 integrase complexed with Mg++ and 1-(5-chloroindol-3-yl)-3-hydroxy-3-(2H-tetrazol-5-yl)-propenone     DOI:10.2210/pdb1qs4/pdb

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Primary Citation       Molecular Description Hide Classification: Transferase Structure Weight: 50802.80   Molecule: PROTEIN (HIV-1 INTEGRASE (E.C.2.7.7.49)) Polymer: 1 Type: polypeptide(L) Length: 154 Chains: A, B, C EC#: 2.7.7.49    Fragment: Catalytic core domain Mutation: F185K, W131E       Source Hide Polymer: 1 Scientific Name: Human immunodeficiency virus 1 Expression System: Escherichia coli bl21         Ligand Chemical Component Hide Identifier Name Formula Interaction View Links 100     1-(5-CHLOROINDOL-3-YL)-3-HYDROXY-3-(2H-TETRAZOL- 5-YL)-PROPENONE C12 H8 Cl N5 O2 Ligand Explorer MG     MAGNESIUM ION Mg Ligand Explorer       Derived Data Hide SCOP Classification v1.75 - (3 Domains) CATH Classification v3.2.0 - (3 Domains) PFAM Classification - (3 Domains) GO Terms - (34 Terms)     Reset Layout

Biological Assembly 1     More Images... View in Jmol Other Viewers close KiNG WebMol QuickPDB FirstGlance Kiosk SimpleViewer Protein Workshop Ligand Explorer Biological assembly 1 assigned by authors Biological assembly 2 assigned by authors         Deposition Summary Hide Authors:   Goldgur, Y.,   Craigie, R.,   Fujiwara, T.,   Yoshinaga,   T,   Davies, D.R. Deposition:   1999-06-25 Release:   1999-11-17 Last Modified (REVDAT):   2008-04-01       Experimental Details Hide Method:   X-RAY DIFFRACTION Experimental Data:   N/A Resolution[Å]: 2.10 R-Value: 0.209 (obs.) R-Free: 0.255 Space Group: C 2 Unit Cell:   Length [Å] Angles [°] a = 76.23 α = 90.00  b = 46.74 β = 105.55  c = 141.36 γ = 90.00