The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein.
Lawrence, M.C., Pilling, P.A., Epa, V.C., Berry, A.M., Ogunniyi, A.D., Paton, J.C.(1998) Structure 6: 1553-1561
- PubMed: 9862808 
- DOI: https://doi.org/10.1016/s0969-2126(98)00153-1
- Primary Citation of Related Structures:  
1PSZ - PubMed Abstract: 
. The surface protein PsaA of the pathogenic bacterium Streptococcus pneumoniae plays an essential role in its virulence. PsaA is a putative ATP-binding cassette-type (ABC-type) binding protein involved in the uptake of Mn2+ and possibly Zn2+ and is considered to be both a potential drug target and and a candidate vaccine component.
Organizational Affiliation: 
Biomolecular Research Institute 343 Royal Parade Parkville Victoria 3052 Australia. mike.lawrence@bioresi.com.au