1NS1

RNA-BINDING DOMAIN OF NON-STRUCTURAL PROTEIN 1 FROM INFLUENZA VIRUS, NMR, 16 STRUCTURES


Experimental Data Snapshot

  • Method: SOLUTION NMR
  • Conformers Calculated: 100 
  • Conformers Submitted: 16 
  • Selection Criteria: LOWEST RESIDUAL CONSTRAINT VIOLATIONS 

wwPDB Validation   3D Report Full Report


This is version 1.3 of the entry. See complete history


Literature

A novel RNA-binding motif in influenza A virus non-structural protein 1.

Chien, C.Y.Tejero, R.Huang, Y.Zimmerman, D.E.Rios, C.B.Krug, R.M.Montelione, G.T.

(1997) Nat Struct Biol 4: 891-895

  • DOI: https://doi.org/10.1038/nsb1197-891
  • Primary Citation of Related Structures:  
    1NS1

  • PubMed Abstract: 

    The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold. Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2' forms a novel arginine-rich nucleic acid binding motif.


Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
NONSTRUCTURAL PROTEIN 1
A, B
73Influenza A virusMutation(s): 0 
Gene Names: J02169
UniProt
Find proteins for P03495 (Influenza A virus (strain A/Udorn/307/1972 H3N2))
Explore P03495 
Go to UniProtKB:  P03495
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP03495
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: SOLUTION NMR
  • Conformers Calculated: 100 
  • Conformers Submitted: 16 
  • Selection Criteria: LOWEST RESIDUAL CONSTRAINT VIOLATIONS 

Structure Validation

View Full Validation Report



Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 1998-01-14
    Type: Initial release
  • Version 1.1: 2008-03-24
    Changes: Version format compliance
  • Version 1.2: 2011-07-13
    Changes: Version format compliance
  • Version 1.3: 2022-02-23
    Changes: Database references, Derived calculations, Other