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Crystal structure of a RAD51-BRCA2 BRC repeat complex
1N0W
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Gene Regulation/antitumor Protein
    Structure Weight: 32823.63
    Molecule: DNA repair protein RAD51 homolog 1
    Polymer: 1 Type: protein Length: 243
    Chains: A
    Fragment: ATPase domain
    Organism: Homo sapiens
    Gene Names: Gene View for RAD51 RAD51A RECA
    UniProtKB: Protein Feature View | Search PDB | Q06609  
    Molecule: Breast cancer type 2 susceptibility protein
    Polymer: 2 Type: protein Length: 35
    Chains: B
    Fragment: BRC repeat type 4
    Organism: Homo sapiens
    Gene Names: Gene View for BRCA2 FACD FANCD1
    UniProtKB: Protein Feature View | Search PDB | P51587  
    Molecule: peptide linker
    Polymer: 3 Type: protein Length: 14
    Chains: L
    Details: this peptide links the BRCA2 to the RAD51
    Molecule: ARTIFICIAL GLY-SER-MSE-GLY PEPTIDE
    Polymer: 4 Type: protein Length: 4
    Chains: C
    Details: this peptide comes from the expression vector and is linked to the N-terminus of BRCA2
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli bl21(de3)  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli bl21(de3)  
    Polymer: 3
    Expression System: Escherichia coli bl21(de3)  
    Polymer: 4
    Expression System: Escherichia coli bl21(de3)  
     
  •   Ligand Chemical Component Hide
     
  •   Modified Residues Hide
    Identifier Formula Parent Type
    MSE
    Search 
    MSE C5 H11 N O2 Se MET lPeptideLinking
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors
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