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Crystal Structure of an RNA Tertiary Domain Essential to HCV IRES-mediated Translation Initiation.
 
 
DOI:10.2210/pdb1kh6/pdb   NDB ID: UR0018
1KH6
 
Primary Citation
spinning wheel
 
 
  •  
    Move Section Molecular Description Hide
    Classification: RNA
    Structure Weight: 17634.80
     
    Molecule:JIIIabc
    Polymer:1Type:polyribonucleotideLength:53
    Chains:A
    Other Details:JIIIabc is the structure of an RNA four-way junction from the Hepatitis C virus internal ribosome entry site. The junction joins domains IIIa, IIIb, and IIIc to the rest of domain III, and is critical for IRES function.
     
     
  •  
    Move Section Source Hide
    Polymer: 1
    Scientific Name: Synthetic construct Go to NCBI Taxonomy entry  
     
     
  •  
    Move Section Modified Residues Hide
    Identifier Name Formula Interaction View Links
    5BU 5-BROMO-URIDINE-5'-MONOPHOSPHATE (parent: U)(type: rnaLinking) C9 H12 Br N2 O9 P Link out to Ligand Expos:5BU Link out to SuperLigands:5BU Link out to SuperHapten:5BU 2D
     
     
 
 
  •  
    Move Section Deposition Summary Hide
    Authors:   Kieft, J.S.,   Zhou, K.,   Grech, A.,   Jubin,   R,   Doudna, J.A.

    Deposition:   2001-11-29
    Release:   2002-04-26
    Last Modified (REVDAT):   2009-02-24
     
     
  •  
    Move Section Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Experimental Data:   Download Structure Factors  [ EDS External Link to EDS ]
    View a histogram of Resolution Resolution[Å]: 2.90
    R-Value: 0.283 (work)
    R-Free: 0.279
    Space Group: P 42 21 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 66.53 α = 90.00 
    b = 66.53 β = 90.00 
    c = 95.85 γ = 90.00