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PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A
1JST
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Complex (protein Kinase/cyclin)
    Structure Weight: 128486.84
    Molecule: CYCLIN-DEPENDENT KINASE-2
    Polymer: 1 Type: protein Length: 298
    Chains: A, C
    EC#: 2.7.11.22   
    Details: PHOSPHORYLATED
    Organism: Homo sapiens
    Gene Names: Gene View for CDK2 CDKN2
    UniProtKB: Protein Feature View | Search PDB | P24941  
    Molecule: CYCLIN A
    Polymer: 2 Type: protein Length: 258
    Chains: B, D
    Fragment: RESIDUES 173-432
    Organism: Homo sapiens
    Gene Names: Gene View for CCNA2 CCN1 CCNA
    UniProtKB: Protein Feature View | Search PDB | P20248  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Spodoptera frugiperda  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    ATP
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    ATP C10 H16 N5 O13 P3
    ADENOSINE-5'-TRIPHOSPHATE
    ATP:1JST
    MN
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    MN Mn
    MANGANESE (II) ION
     
  •   Modified Residues Hide
    Identifier Formula Parent Type
    TPO
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    TPO C4 H10 N O6 P THR lPeptideLinking
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PQS (software)
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  •   Deposition Summary Hide
    Authors:   Russo, A.A.,  Jeffrey, P.D.,  Pavletich, N.P.

    Deposition:   1996-07-03
    Release:   1997-01-11
    Last Modified (REVDAT):   2011-07-13
     
  •   Revision History    Hide
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    2011-07-13
    Biological assembly
    2011-07-13
    Version format compliance
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
    N/A
    Resolution[Å]:   2.60
    R-Value: 0.200 (work)
    R-Free: n/a
    Space Group: P 21 21 21
    Unit Cell:
      Length [Å] Angles [°]
    a = 139.60 α = 90.00 
    b = 149.10 β = 90.00 
    c = 74.20 γ = 90.00