Crystal Structure of a Human Tcf-4 / beta-Catenin Complex
1JPW
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  •   Molecular Description Hide
    Classification: Cell Adhesion
    Structure Weight: 192513.59
    Molecule: BETA-CATENIN
    Polymer: 1 Type: protein Length: 540
    Chains: A, B, C
    Organism: Homo sapiens
    Gene Names: Gene View for CTNNB1 CTNNB OK/SW-cl.35 PRO2286
    UniProtKB: Protein Feature View | Search PDB | P35222  
    Molecule: transcription factor 7-like 2
    Polymer: 2 Type: protein Length: 49
    Chains: D, E, F
    Organism: Homo sapiens
    Gene Names: Gene View for TCF7L2 Gene View for TCF4
    UniProtKB: Protein Feature View | Search PDB | Q9NQB0  
     
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  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli bl21(de3)  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli bl21(de3)  
     
  •   Related PDB Entries Hide
    Identifier Details
    1G3J   Crystal Structure Of The Xtcf3-Cbd/-Catenin Armadillo Repeat Complex 
    1I7W   beta-Catenin/Phosphorylated E-Cadherin Complex 
    1I7X   beta-Catenin/E-Cadherin Complex 
    2bct   beta-catenin armadillo repeat region 
    3bct   beta-catenin armadillo repeat region 
     
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Data in orange boxes are gathered from external resources (when available).
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PISA (software)
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  •   Deposition Summary Hide
    Authors:   Poy, F.,  Lepourcelet, M.,  Shivdasani, R.A.,  Eck, M.J.

    Deposition:   2001-08-03
    Release:   2001-12-05
    Last Modified (REVDAT):   2009-02-24
     
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    2011-07-13
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  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
    N/A
    Resolution[Å]:   2.50
    R-Value: 0.305 (obs.)
    R-Free: 0.390
    Space Group: C 1 2 1
    Unit Cell:
      Length [Å] Angles [°]
    a = 376.53 α = 90.00 
    b = 92.65 β = 95.98 
    c = 49.25 γ = 90.00