Crystal structure of a human insulin peptide-HLA-DQ8 complex
1JK8
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Immune System
    Structure Weight: 44768.54
    Molecule: MHC class II HLA-DQ8
    Polymer: 1 Type: protein Length: 181
    Chains: A
    Fragment: alpha chain (DQA1*0301)
    Organism: Homo sapiens
    Gene Name: Gene View for HLA-DQA1
    UniProtKB: Protein Feature View | Search PDB | P01909  
    Molecule: MHC class II HLA-DQ8
    Polymer: 2 Type: protein Length: 190
    Chains: B
    Fragment: beta chain (DQB1*0302)
    Organism: Homo sapiens
    Gene Names: Gene View for HLA-DQB1 HLA-DQB
    UniProtKB: Protein Feature View | Search PDB | P01920  
    Molecule: insulin B peptide
    Polymer: 3 Type: protein Length: 14
    Chains: C
    Fragment: peptide (9-SHLVEALYLVCGERG-23)
    Organism: Homo sapiens
    Gene Name: Gene View for INS
    UniProtKB: Protein Feature View | Search PDB | P01308  
     
  •   Structure Validation Hide

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  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Spodoptera frugiperda  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Spodoptera frugiperda  
    Polymer: 3
    Scientific Name: Synthetic construct (Homo sapiens)   Taxonomy    
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    NAG
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    NAG C8 H15 N O6
    N-ACETYL-D-GLUCOSAMINE
    NAG:1JK8
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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