1FQ3
CRYSTAL STRUCTURE OF HUMAN GRANZYME B
- PDB DOI: https://doi.org/10.2210/pdb1FQ3/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens
- Expression System: Spodoptera frugiperda
- Mutation(s): No 
- Deposited: 2000-09-03 Released: 2001-01-31 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 3.10 Å
wwPDB Validation   3D Report Full Report
This is version 2.1 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
GRANZYME B | 227 | Homo sapiens | Mutation(s): 0  EC: 3.4.21.79 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P10144 (Homo sapiens) Explore P10144  Go to UniProtKB:  P10144 | |||||
PHAROS:  P10144 GTEx:  ENSG00000100453  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P10144 | ||||
Sequence AnnotationsExpand | |||||
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Oligosaccharides
Small Molecules
Ligands 1 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
SO4 Query on SO4 | E [auth A], F [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 3.10 Å
- Space Group: P 21 21 21
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 41.74 | α = 90 |
b = 114.31 | β = 90 |
c = 135.52 | γ = 90 |
Software Name | Purpose |
---|---|
MOSFLM | data reduction |
SCALA | data scaling |
AMoRE | phasing |
X-PLOR | refinement |
CCP4 | data scaling |
Entry History 
Deposition Data
- Released Date: 2001-01-31  Deposition Author(s): Estebanez-Perpina, E., Fuentes-Prior, P., Belorgey, D., Rubin, H., Bode, W.
Revision History (Full details and data files)
- Version 1.0: 2001-01-31
Type: Initial release - Version 1.1: 2008-04-27
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Non-polymer description, Version format compliance - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Advisory, Atomic model, Data collection, Derived calculations, Non-polymer description, Structure summary - Version 2.1: 2024-04-03
Changes: Advisory, Data collection, Database references, Refinement description, Structure summary