STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING
1E8X

Entry 1E8X supersedes 1QMM

Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Phosphoinositide 3 Kinase Gamma
    Structure Weight: 112034.89
    Molecule: PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT
    Polymer: 1 Type: protein Length: 961
    Chains: A
    EC#: 2.7.1.153    2.7.11.1   
    Fragment: PI3-KINASE P110 SUBUNIT GAMMA
    Mutation: YES
    Details: LUTETIUM DERIVATIVE
    Organism: Sus scrofa
    Gene Name: Gene View for PIK3CG
    UniProtKB: Protein Feature View | Search PDB | O02697  
     
  •   Structure Validation Hide

    View the full validation report  

     

  • MolProbity Ramachandran Plot
     

  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Sus scrofa   Taxonomy   Common Name: Wild boar Expression System: Spodoptera frugiperda  
     
  •   Related PDB Entries Hide
    Identifier Details
    1E7U   STRUCTURE DETERMINANTS OF PHOSPHOINOSITIDE 3-KINASE INHIBITION BY WORTMANNIN, LY294002, QUERCETIN, MYRICETIN AND STAUROSPORINE 
    1E7V   STRUCTURE DETERMINANTS OF PHOSPHOINOSITIDE 3-KINASE INHIBITION BY WORTMANNIN, LY294002, QUERCETIN, MYRICETIN AND STAUROSPORINE 
    1E8W   STRUCTURE DETERMINANTS OF PHOSPHOINOSITIDE 3-KINASE INHIBITION BY WORTMANNIN, LY294002, QUERCETIN, MYRICETIN AND STAUROSPORINE 
    1QMM   STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    ATP
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    ATP C10 H16 N5 O13 P3
    ADENOSINE-5'-TRIPHOSPHATE
    ATP:1E8X
    LU
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    LU Lu
    LUTETIUM (III) ION
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
  Biological Assembly       
Biological assembly 1 generated by PQS (software)
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