1C5G

PLASMINOGEN ACTIVATOR INHIBITOR-1

PDB DOI: https://doi.org/10.2210/pdb1C5G/pdb

Classification: BLOOD CLOTTING
Organism(s): Homo sapiens
Expression System: Escherichia coli
Mutation(s): No

Deposited: 1999-12-07 Released: 1999-12-17
Deposition Author(s): Goldsmith, E.J.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 2.60 Å

wwPDB Validation 3D Report Full Report

This is version 1.3 of the entry. See complete history.

Literature

Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition.

Tucker, H.M., Mottonen, J., Goldsmith, E.J., Gerard, R.D.

(1995) Nat Struct Biol 2: 442-445

PubMed: 7664104 Search on PubMed
DOI: https://doi.org/10.1038/nsb0695-442
Primary Citation of Related Structures:
1C5G

Macromolecule Content

Total Structure Weight: 45.11 kDa
Atom Count: 3,013
Modelled Residue Count: 379
Deposited Residue Count: 402
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
PLASMINOGEN ACTIVATOR INHIBITOR-1	A	402	Homo sapiens	Mutation(s): 0
UniProt & NIH Common Fund Data Resources
Find proteins for P05121 (Homo sapiens) Explore P05121 Go to UniProtKB: P05121
PHAROS: P05121 GTEx: ENSG00000106366
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P05121
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 2.60 Å
Space Group: C 1 2 1

Unit Cell:

Length ( Å )	Angle ( ˚ )
a = 157.59	α = 90
b = 47.84	β = 107.78
c = 62.88	γ = 90

Software Package:

Software Name	Purpose
X-PLOR	model building
X-PLOR	refinement
SDMS	data reduction
FAST	data scaling
X-PLOR	phasing

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 1999-12-17

Deposition Author(s):

Goldsmith, E.J.

Revision History (Full details and data files)

Version 1.0: 1999-12-17
Type: Initial release
Version 1.1: 2008-04-26
Changes: Version format compliance
Version 1.2: 2011-07-13
Changes: Version format compliance
Version 1.3: 2023-12-27
Changes: Data collection, Database references

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.