Download MendeleyHUMAN CATHEPSIN G
Medrano, F.J., Bode, W., Banbula, A., Potempa, J.To be published.
1AU8
HUMAN CATHEPSIN G
- PDB DOI: https://doi.org/10.2210/pdb1AU8/pdb
- Classification: HYDROLASE/HYDROLASE INHIBITOR
- Organism(s): Homo sapiens
- Mutation(s): No
- Deposited: 1997-09-12 Released: 1998-10-14
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.251
- R-Value Work: 0.186
- R-Value Observed: 0.186
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| CATHEPSIN G | 224 | Homo sapiens | Mutation(s): 0 EC: 3.4.21.20 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P08311 (Homo sapiens) Explore P08311 Go to UniProtKB: P08311 | |||||
PHAROS: P08311 GTEx: ENSG00000100448 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P08311 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 0H8 Query on 0H8 | B [auth A] | N-(3-carboxypropanoyl)-L-valyl-N-[(1R)-5-amino-1-phosphonopentyl]-L-prolinamide C19 H35 N4 O8 P POVVCGMAFFRCCC-LXZKKBNFSA-N |  | ||
Biologically Interesting Molecules (External Reference) 1 Unique
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| ID | Chains | Name | Type/Class | 2D Diagram | 3D Interactions |
| PRD_000756 (0H8) Query on PRD_000756 | B [auth A] | N-(3-carboxypropanoyl)-L-valyl-N-[(1R)-5-amino-1-phosphonopentyl]-L-prolinamide | Peptide-like / Inhibitor | | |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.251
- R-Value Work: 0.186
- R-Value Observed: 0.186
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 40.23 | α = 90 |
| b = 63.46 | β = 90 |
| c = 80.21 | γ = 90 |
| Software Name | Purpose |
|---|---|
| MOSFLM | data reduction |
| ROTAVATA/AGROVATA | data reduction |
| X-PLOR | model building |
| X-PLOR | refinement |
| CCP4 | data scaling |
| ROTAVATA) | data scaling |
| X-PLOR | phasing |
Entry History
Deposition Data
- Released Date: 1998-10-14 Deposition Author(s): Medrano, F.J., Bode, W., Banbula, A., Potempa, J.
Revision History (Full details and data files)
- Version 1.0: 1998-10-14
Type: Initial release - Version 1.1: 2008-03-24
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Atomic model, Database references, Derived calculations, Non-polymer description, Structure summary, Version format compliance - Version 1.3: 2012-12-12
Changes: Other
