1AIL

N-TERMINAL FRAGMENT OF NS1 PROTEIN FROM INFLUENZA A VIRUS


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.90 Å
  • R-Value Free: 0.229 
  • R-Value Work: 0.182 

wwPDB Validation   3D Report Full Report


This is version 1.3 of the entry. See complete history


Literature

Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein.

Liu, J.Lynch, P.A.Chien, C.Y.Montelione, G.T.Krug, R.M.Berman, H.M.

(1997) Nat Struct Biol 4: 896-899

  • DOI: https://doi.org/10.1038/nsb1197-896
  • Primary Citation of Related Structures:  
    1AIL

  • PubMed Abstract: 

    The nonstructural protein (NS1 protein) of the influenza A virus binds to several types of RNAs. X-ray crystallographic analysis of the RNA-binding domain reveals a unique topology for the monomer as well as a novel six-helix structure for the dimer.


Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
NONSTRUCTURAL PROTEIN NS173Influenza A virus (A/Udorn/307/1972(H3N2))Mutation(s): 0 
UniProt
Find proteins for P03495 (Influenza A virus (strain A/Udorn/307/1972 H3N2))
Explore P03495 
Go to UniProtKB:  P03495
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP03495
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.90 Å
  • R-Value Free: 0.229 
  • R-Value Work: 0.182 
  • Space Group: P 43 21 2
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 38.651α = 90
b = 38.651β = 90
c = 82.928γ = 90
Software Package:
Software NamePurpose
PHASESphasing
SOLOMONphasing
REFMACrefinement
DENZOdata reduction
SCALEPACKdata scaling

Structure Validation

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Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 1997-10-22
    Type: Initial release
  • Version 1.1: 2008-03-24
    Changes: Version format compliance
  • Version 1.2: 2011-07-13
    Changes: Derived calculations, Version format compliance
  • Version 1.3: 2024-02-07
    Changes: Data collection, Database references, Structure summary