Download MendeleyLigand-Induced Conformational Changes in a Catalytic Antibody: Comparison of the Bound and Unbound Structure of Fab 5C8
Gruber, K., Heine, A., Stura, E.A., Shevlin, C.G., Wilson, I.A.To be published.
15C8
CATALYTIC ANTIBODY 5C8, FREE FAB
- PDB DOI: https://doi.org/10.2210/pdb15C8/pdb
- Classification: CATALYTIC ANTIBODY
- Organism(s): Mus musculus
- Mutation(s): No
- Deposited: 1998-03-18 Released: 1999-03-23
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.251
- R-Value Work: 0.190
- R-Value Observed: 0.190
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| IGG 5C8 FAB (LIGHT CHAIN) | A [auth L] | 213 | Mus musculus | Mutation(s): 0 |  |
UniProt | |||||
Find proteins for P01837 (Mus musculus) Explore P01837 Go to UniProtKB: P01837 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P01837 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| IGG 5C8 FAB (HEAVY CHAIN) | B [auth H] | 217 | Mus musculus | Mutation(s): 0 |  |
UniProt | |||||
Find proteins for P01869 (Mus musculus) Explore P01869 Go to UniProtKB: P01869 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P01869 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.251
- R-Value Work: 0.190
- R-Value Observed: 0.190
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 201 | α = 90 |
| b = 80.5 | β = 98.7 |
| c = 39.3 | γ = 90 |
| Software Name | Purpose |
|---|---|
| XENGEN | data collection |
| XENGEN | data reduction |
| AMoRE | phasing |
| MERLOT | phasing |
| X-PLOR | refinement |
| XENGEN | data scaling |
Entry History
Deposition Data
- Released Date: 1999-03-23 Deposition Author(s): Gruber, K., Wilson, I.A.
Revision History (Full details and data files)
- Version 1.0: 1999-03-23
Type: Initial release - Version 1.1: 2008-03-24
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2023-08-02
Changes: Database references, Refinement description
