Download MendeleyCrystal Structure of Camp Receptor Protein from Mycobacterium Tuberculosis in Complex with DNA and cAMP
Akhter, Y., Pogenberg, V., Hasnain, S.E., Wilmanns, M.To be published.
3MZH
Crystal structure of cAMP receptor protein from mycobacterium tuberculosis in complex with cAMP and its DNA binding element
- PDB DOI: https://doi.org/10.2210/pdb3MZH/pdb
- NAKB: 3MZH
- Classification: TRANSCRIPTION/DNA
- Organism(s): Mycobacterium tuberculosis H37Rv
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2010-05-12 Released: 2011-06-08
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.90 Å
- R-Value Free: 0.279
- R-Value Work: 0.247
- R-Value Observed: 0.248
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY CRP/FNR-FAMILY) | 225 | Mycobacterium tuberculosis H37Rv | Mutation(s): 0 Gene Names: Rv3676 |  | |
UniProt | |||||
Find proteins for P9WMH3 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P9WMH3 Go to UniProtKB: P9WMH3 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P9WMH3 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar nucleic acids by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Length | Organism | Image | |
| 5'-D(P*AP*AP*AP*TP*GP*TP*GP*AP*TP*CP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*G)-3' | 21 | N/A |  | ||
Sequence AnnotationsExpand | |||||
| |||||
Find similar nucleic acids by: Sequence | 3D Structure
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| CMP Query on CMP | E [auth A], F [auth B], G [auth B] | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE C10 H12 N5 O6 P IVOMOUWHDPKRLL-KQYNXXCUSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.90 Å
- R-Value Free: 0.279
- R-Value Work: 0.247
- R-Value Observed: 0.248
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 66.13 | α = 90 |
| b = 61.25 | β = 104.29 |
| c = 89.94 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DNA | data collection |
| Auto-Rickshaw | phasing |
| PHASER | phasing |
| PHENIX | refinement |
| iMOSFLM | data reduction |
| SCALA | data scaling |
Entry History
Deposition Data
- Released Date: 2011-06-08 Deposition Author(s): Akhter, Y., Wilmanns, M.
Revision History (Full details and data files)
- Version 1.0: 2011-06-08
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2011-07-20
Changes: Other - Version 1.3: 2023-11-01
Changes: Data collection, Database references, Derived calculations, Refinement description
