3HKO

Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.80 Å
  • R-Value Free: 0.246 
  • R-Value Work: 0.201 
  • R-Value Observed: 0.204 

wwPDB Validation   3D Report Full Report


Ligand Structure Quality Assessment 


This is version 1.3 of the entry. See complete history


Literature

Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40

Wernimont, A.K.Hutchinson, A.Wasney, G.Vedadi, M.MacKenzie, F.Kozieradzki, I.Cossar, D.Weigelt, J.Edwards, A.M.Arrowsmith, C.H.Bountra, C.Botchkarev, A.Hui, R.Amani, M.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands345Cryptosporidium parvum Iowa IIMutation(s): 0 
Gene Names: cgd7_40
UniProt
Find proteins for Q5CZ29 (Cryptosporidium parvum (strain Iowa II))
Explore Q5CZ29 
Go to UniProtKB:  Q5CZ29
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5CZ29
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.80 Å
  • R-Value Free: 0.246 
  • R-Value Work: 0.201 
  • R-Value Observed: 0.204 
  • Space Group: P 21 21 21
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 54.48α = 90
b = 63.045β = 90
c = 84.041γ = 90
Software Package:
Software NamePurpose
DENZOdata reduction
SCALEPACKdata scaling
REFMACrefinement
PDB_EXTRACTdata extraction
MacCHESSdata collection
PHASERphasing
RESOLVEphasing

Structure Validation

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Ligand Structure Quality Assessment 


Entry History 

Revision History  (Full details and data files)

  • Version 1.0: 2009-06-02
    Type: Initial release
  • Version 1.1: 2011-07-13
    Changes: Non-polymer description, Version format compliance
  • Version 1.2: 2017-11-01
    Changes: Advisory, Refinement description
  • Version 1.3: 2023-09-06
    Changes: Advisory, Data collection, Database references, Derived calculations, Refinement description