Download MendeleyHuman Ubiquitin-activating Enzyme 5 in Complex with AMPPNP
Walker, J.R., Bacik, J.P., Li, Y., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S.To be published.
3GUC
Human Ubiquitin-activating Enzyme 5 in Complex with AMPPNP
- PDB DOI: https://doi.org/10.2210/pdb3GUC/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2009-03-29 Released: 2009-05-26
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.25 Å
- R-Value Free: 0.255
- R-Value Work: 0.203
- R-Value Observed: 0.206
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Ubiquitin-like modifier-activating enzyme 5 | 292 | Homo sapiens | Mutation(s): 0 Gene Names: UBA5, UBE1DC1 EC: 2.7.7 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9GZZ9 (Homo sapiens) Explore Q9GZZ9 Go to UniProtKB: Q9GZZ9 | |||||
PHAROS: Q9GZZ9 GTEx: ENSG00000081307 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9GZZ9 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ANP Query on ANP | D [auth A] | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER C10 H17 N6 O12 P3 PVKSNHVPLWYQGJ-KQYNXXCUSA-N |  | ||
| ZN Query on ZN | C [auth A], E [auth B] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.25 Å
- R-Value Free: 0.255
- R-Value Work: 0.203
- R-Value Observed: 0.206
- Space Group: P 32 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 77.394 | α = 90 |
| b = 77.394 | β = 90 |
| c = 205.892 | γ = 120 |
| Software Name | Purpose |
|---|---|
| HKL-3000 | data collection |
| PHASER | phasing |
| REFMAC | refinement |
| HKL-3000 | data reduction |
| HKL-3000 | data scaling |
Entry History
Deposition Data
- Released Date: 2009-05-26 Deposition Author(s): Walker, J.R., Bacik, J.P., Li, Y., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2009-05-26
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2014-11-12
Changes: Structure summary - Version 1.3: 2023-09-06
Changes: Data collection, Database references, Derived calculations, Refinement description
