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Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(G92A) from Vibrio cholerae
Biology and Chemistry Report
3TZK
  •   Structure Details   Hide

    Structure Keywords

    Keywords OXIDOREDUCTASE
    Text Vibrio cholerae, 3-ketoacyl-(acyl-carrier-protein) reductase, FabG, OXIDOREDUCTASE, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID

    Polymeric Molecules

    Chain A,B
    Description 3-oxoacyl-[acyl-carrier protein] reductase 
    Mutation G92A 
    Nonstandard Linkage no 
    Nonstandard Monomers no 
    Polymer Type polypeptide(L) 
    Formula Weight 26372.3 
    Source Method genetically manipulated  

    Ligands and Prosthetic Groups

    ID Name Chemical Formula Weight Ligand Structure
    SO4  SULFATE ION  O4 S   96.06  View 
    UNX  UNKNOWN ATOM OR ION  X   0.00  View 
     
  •   Protein Details   Hide

    UniProtKB Information

    Chain SWS/UNP ID SWS/UNP Accession(s)
    A,B C3NP04_VIBCJ C3NP04     

    Keywords and Names

    Chain(s) RCSB Name UniProtKB Name UniProtKB Keywords

    EC, Associated Pathways and Catalytic Sites

    Chain(s) IUBMB KEGG BioCyc
    A B  1.1.1.100      
    C: Cellular Location | F: Molecular Function | P: Biological Process
    Chain A,B
    GO ID   Ontology GO Term Definition
    55114   Oxidation Reduction Process  A Metabolic Process That Results in the Removal or Addition of One or More Electrons to or From a Substance with or Without the Concomitant Removal or Addition of a Proton or Protons. 
    166   Nucleotide Binding  Interacting Selectively and Non Covalently with a Nucleotide Any Compound Consisting of a Nucleoside That Is Esterified with (ortho)phosphate or an Oligophosphate At Any Hydroxyl Group On the Ribose or Deoxyribose. 
    16491   Oxidoreductase Activity  Catalysis of an Oxidation Reduction (redox) Reaction a Reversible Chemical Reaction in Which the Oxidation State of an Atom or Atoms Within a Molecule Is Altered. One Substrate Acts As a Hydrogen or Electron Donor and Becomes Oxidized While the Other Acts As Hydrogen or Electron Acceptor and Becomes Reduced. 


     
  •   Gene Details   Hide

    Genetic Source

    Chain A,B
    Scientific Name Vibrio cholerae  
    Strain MJ-1236
    Gene vc2021, vcd_002346
    Host Scientific Name Escherichia coli  
    Host Strain Bl21 Codonplus(de3) Ripl
    Host Vector Type Plasmid
    Host Plasmid Name pMCSG7