POP-OUT | CLOSE
MyPDB Login - Username: Password:

About: MyPDB stores and automatically runs your favorite queries. Email alerts are sent when matching structures are found.

    MyPDB Login
MyPDB: Login | Register
RCSB PDB Protein Data Bank | Home A Member of the wwPDB

An Information Portal to Biological Macromolecular Structures

As of Tuesday Feb 02, 2010 at 4 PM PST there are 63093 Structures RSS Feed for the Latest Released Structures Help | Latest Released  |  PDB Statistics Help | PDB Statistics
RCSB PDB Protein Data Bank | Home

Print Options: BW Safe Color Safe Print




URL:
 
 
Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and CORTISONE. Resolution 1.90 A.
 
 
DOI:10.2210/pdb3cmf/pdb
3CMF
 
Primary Citation
spinning wheel
 
 
  •  
    Move Section Molecular Description Hide
    Classification: Oxidoreductase
    Structure Weight: 81402.89
     
    Molecule:3-oxo-5-beta-steroid 4-dehydrogenase
    Polymer:1Type:polypeptide(L)Length:346
    Chains:A, B
    EC#:1.3.1.3 Go to IUBMB EC entry  
     
     
  •  
    Move Section Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens Go to NCBI Taxonomy entry Common Name: Human Expression System: Escherichia coli  
     
     
  •  
    Move Section Related PDB Entries Hide
    Id Details
    3BUR  Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and TESTOSTERONE 
    3COT  Same protein in complex with progesterone and nadp 
     
     
  •  
    Move Section Ligand Chemical Component Hide
    Identifier Name Formula Interaction View Links
    NAP     NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE C21 H28 N7 O17 P3 3DLigand Explorer Link out to Ligand Expos:NAP Link out to SuperLigands:NAP Link out to SuperHapten:NAP
    PDN     17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE C21 H26 O5 3DLigand Explorer Link out to Ligand Expos:PDN Link out to SuperLigands:PDN Link out to SuperHapten:PDN
     
     
  •  
    Move Section Derived Data Hide
     
     
Reset Layout
 
< Biological Assembly 1    Help >
Help | Display Options
Biological assembly 1 assigned by authors and generated by PISA (software)
 
 
 
  •  
    Move Section Deposition Summary Hide
    Authors:   Di Costanzo, L.,   Drury, J.,   Penning, T.M.,   Christianson, D.W.

    Deposition:   2008-03-21
    Release:   2008-04-08
    Last Modified (REVDAT):   2009-02-24
     
     
  •  
    Move Section Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Experimental Data:   Download Structure Factors  [ EDS External Link to EDS ]
    View a histogram of Resolution Resolution[Å]: 1.90
    R-Value: 0.195 (obs.)
    R-Free: 0.223
    Space Group: P 21 21 21
    Unit Cell:
      Length [Å] Angles [°]
    a = 49.72 α = 90.00 
    b = 109.20 β = 90.00 
    c = 127.84 γ = 90.00