Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and CORTISONE. Resolution 1.90 A.
3CMF
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Oxidoreductase
    Structure Weight: 81402.89
    Molecule: 3-oxo-5-beta-steroid 4-dehydrogenase
    Polymer: 1 Type: protein Length: 346
    Chains: A, B
    EC#: 1.3.1.3   
    Organism: Homo sapiens
    Gene Names: Gene View for AKR1D1 SRD5B1
    UniProtKB: Protein Feature View | Search PDB | P51857  
     
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  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
     
  •   Related PDB Entries Hide
    Identifier Details
    3BUR   Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and TESTOSTERONE 
    3COT   Same protein in complex with progesterone and nadp 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    NAP
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    NAP C21 H28 N7 O17 P3
    NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
    PDN
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    PDN C21 H26 O5
    17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE
    PDN:3CMF
     
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Data in orange boxes are gathered from external resources (when available).
  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PISA (software)
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