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Crystal structure of human Delta(4)-3-ketosteroid 5-beta-reductase in complex with NADP and HEPES. Resolution: 1.35 A.
3BUV
Primary Citation
 
 
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  •   Molecular Description Hide
    Classification: Oxidoreductase
    Structure Weight: 76765.71
    Molecule: 3-oxo-5-beta-steroid 4-dehydrogenase
    Polymer: 1 Type: protein Length: 326
    Chains: A, B
    EC#: 1.3.1.3   
    Organism Homo sapiens
    Gene Names AKR1D1 SRD5B1
    UniProtKB:   Protein Feature View | Search PDB | P51857  
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
     
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    Identifier Details
    3BUR  Same enzyme in complex with NADP and TESTOSTERONE 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name Interactions
    EPE
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    Download      		EPE C8 H18 N2 O4 S
    4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
    		EPE:3BUV
    GOL
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    Download      		GOL C3 H8 O3
    GLYCEROL
    NAP
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    Download      		NAP C21 H28 N7 O17 P3
    NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
     
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  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
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  Biological Assembly 1       
Biological assembly 1 assigned by authors and generated by PISA (software)
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