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THERMOSTABILISED HUMAN A2A RECEPTOR WITH ADENOSINE BOUND
2YDO
Primary Citation
 
 
  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Molecular Description Hide
    Classification: Receptor
    Structure Weight: 36907.11
    Molecule: ADENOSINE RECEPTOR A2A
    Polymer: 1 Type: protein Length: 325
    Chains: A
    Fragment: RESIDUES 1-317
    Mutation: YES
    Organism Homo sapiens
    Gene Names ADORA2A ADORA2
    UniProtKB:   Protein Feature View | Search PDB | P29274  
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Trichoplusia ni  
     
  •   Related PDB Entries Hide
    Identifier Details
    1MMH  MOLECULAR MODEL OF THE HUMAN A2A ADENOSINE RECEPTOR 
    1UPE  MODELING THE ADENOSINE RECEPTORS: COMPARISON OF THE BINDING DOMAINS OF A2A AGONISTS AND ANTAGONISTS 
    2YDV  THERMOSTABILISED HUMAN A2A RECEPTOR WITH NECA BOUND 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name Interactions
    ADN
    Search 
    Download      		ADN C10 H13 N5 O4
    ADENOSINE
    		ADN:2YDO
    SOG
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    Download      		SOG C14 H28 O5 S
    2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO- PYRAN-3,4,5-TRIOL
     
  •   External Ligand Annotations Hide
    Identifier   Binding Affinity (Sequence Identity %)
    ADN
    Search 
    Download      		ADN
    N/Ain BindingDB
    N/Ain BindingMoad
    Ki: 30.9 nM - data from PDBbind  
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
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  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA (software)
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