Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), apo form DOI:10.2210/pdb2ihw/pdb

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Primary Citation       Related Citations in PDB Entry (REMARK 1) Hide     Molecular Description Hide Classification: Transferase Structure Weight: 231184.56 Molecule: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex Polymer: 1 Type: protein Length: 262 Chains: A, B, C, D, E, F, G, H EC#: 2.3.1.168    Fragment: core (catalytic) domain Organism Bos taurus Gene Name DBT UniProtKB:   Protein Feature View | Search PDB | P11181         Source Hide Polymer: 1 Scientific Name: Bos taurus   Taxonomy   Common Name: Cattle Expression System: Escherichia coli bl21(de3)       Related PDB Entries Hide Identifier Details 2II3  Crystal structure of cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Oxidized Coenzyme A-bound form  2II4  Crystal structure of cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Coenzyme A-bound form  2II5  Crystal structure of cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Isobutyryl-Coenzyme A-bound form      Ligand Chemical Component Hide Identifier Formula Name Interactions ACT Search  Download  C2 H3 O2 ACETATE ION   Ligand Explorer CL Search  Download  Cl CHLORIDE ION   Ligand Explorer     External Domain Annotations Hide Pfam Classification: 1 Domain - data from Pfam       Structural Biology Knowledgebase Data Hide     Data in orange boxes are gathered from external resources (when available). Reset Layout

Biological Assembly            View in 3D More Images... Biological assembly 1 assigned by authors and generated by PISA (software) Downloadable viewers: Simple Viewer Protein Workshop Ligand Explorer Kiosk Viewer Other Viewers  KiNG WebMol QuickPDB FirstGlance         MyPDB Personal Annotations Hide     Deposition Summary Hide Authors:   Kato, M.,  Wynn, R.M.,  Chuang, J.L.,  Brautigam, C.A.,  Custorio, M.,  Chuang, D.T. Deposition:   2006-09-27 Release:   2006-12-26 Last Modified (REVDAT):   2011-07-13     Revision History    Hide Mouse over text for details 2011-07-13 Version format compliance 2011-07-13 Biological assembly     Experimental Details Hide Method:   X-RAY DIFFRACTION Exp. Data:   Structure Factors Resolution[Å]:   2.70 R-Value: 0.186 (obs.) R-Free: 0.257 Space Group: H 3 Unit Cell:   Length [Å] Angles [°] a = 194.65 α = 90.00  b = 194.65 β = 90.00  c = 171.93 γ = 120.00