CRYSTAL STRUCTURE OF AN HSP90-SBA1 CLOSED CHAPERONE COMPLEX     DOI:10.2210/pdb2cg9/pdb

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Primary Citation       Molecular Description Hide Classification: Chaperone Structure Weight: 188727.17   Molecule: ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 Polymer: 1 Type: polypeptide(L) Length: 677 Chains: A, B Fragment: RESIDUES 1-677 Other Details: CHARGED LINKER REMOVED BETWEEN 221 AND 255 AND REPLACE BY LQHMASVD Molecule: CO-CHAPERONE PROTEIN SBA1 Polymer: 2 Type: polypeptide(L) Length: 134 Chains: X, Y Fragment: RESIDUES 1-134 Mutation: YES       Source Hide Polymer: 1 Scientific Name: Saccharomyces cerevisiae Common Name: Baker's yeast Expression System: Escherichia coli   Polymer: 2 Scientific Name: Saccharomyces cerevisiae Common Name: Baker's yeast Expression System: Escherichia coli         Related PDB Entries Hide Id Details 1A4H  STRUCTURE OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE IN COMPLEX WITH GELDANAMYCIN  1AH6  STRUCTURE OF THE TETRAGONAL FORM OF THE N -TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE  1AH8  STRUCTURE OF THE ORTHORHOMBIC FORM OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE  1AM1  ATP BINDING SITE IN THE HSP90 MOLECULAR CHAPERONE  1AMW  ADP BINDING SITE IN THE HSP90 MOLECULAR CHAPERONE  1BGQ  RADICICOL BOUND TO THE ATP BINDING SITE OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE  1HK7  MIDDLE DOMAIN OF HSP90  1US7  COMPLEX OF HSP90 AND P50  1USU  THE STRUCTURE OF THE COMPLEX BETWEEN AHA1 AND HSP90  1USV  THE STRUCTURE OF THE COMPLEX BETWEEN AHA1 AND HSP90  2AKP  HSP90 DELTA24-N210 MUTANT  2BRC  STRUCTURE OF A HSP90 INHIBITOR BOUND TO THE N-TERMINUS OF YEAST HSP90.  2BRE  STRUCTURE OF A HSP90 INHIBITOR BOUND TO THE N-TERMINUS OF YEAST HSP90.  2CGE  STRUCTURE OF A HSP90-SBA1 CLOSED CHAPERONE COMPLEX.        Ligand Chemical Component Hide Identifier Name Formula Interaction View Links ATP     ADENOSINE-5'-TRIPHOSPHATE C10 H16 N5 O13 P3 Ligand Explorer       Derived Data Hide PFAM Classification - (4 Domains) GO Terms - (21 Terms)     Reset Layout

Biological Assembly     More Images... View in Jmol Other Viewers close KiNG WebMol QuickPDB FirstGlance Kiosk SimpleViewer Protein Workshop Ligand Explorer Biological assembly assigned by authors and generated by PQS (software)         Deposition Summary Hide Authors:   Ali, M.M.U.,   Roe, S.M.,   Prodromou, C.,   Pearl, L.H. Deposition:   2006-03-01 Release:   2006-04-12 Last Modified (REVDAT):   2009-02-24       Experimental Details Hide Method:   X-RAY DIFFRACTION Experimental Data:    [ EDS ] Resolution[Å]: 3.10 R-Value: 0.314 (obs.) R-Free: 0.353 Space Group: P 41 21 2 Unit Cell:   Length [Å] Angles [°] a = 126.73 α = 90.00  b = 126.73 β = 90.00  c = 279.78 γ = 90.00        Structure Links Hide Molecule of the Month Features: Hsp90