Crystal structure (G) of native cationic cyclization antibody 4C6 fab at pH 8.5 with a data set collected at APS beamline 19-ID DOI:10.2210/pdb1rup/pdb

1RUP   Display Files  close FASTA Sequence PDB File PDB File (Header) mmCIF File mmCIF File (Header) PDBML/XML File PDBML/XML File (Header)   Download Files  close FASTA Sequence PDB File (Text) PDB File (gz) mmCIF File mmCIF File (gz) PDBML/XML File PDBML/XML File (gz) Structure Factor (Text) Structure Factor (gz) Biological Assembly (gz) (A+S)   Share this Page  close Facebook Twitter LinkedIn Email Link this Page

Primary Citation       Related Citations in PDB Entry (REMARK 1) Hide     Molecular Description Hide Classification: Immune System Structure Weight: 48526.40 Molecule: immunoglobulin igg2a, heavy chain Polymer: 1 Type: protein Length: 219 Chains: L Fragment: fab Organism Mus musculus UniProtKB:   Protein Feature View | Search PDB | Q8K0F8     Molecule: immunoglobulin igg2a, light chain Polymer: 2 Type: protein Length: 222 Chains: H Fragment: fab Organism Mus musculus Gene Name Igh-1a UniProtKB:   Protein Feature View | Search PDB | P01865         Source Hide Polymer: 1 Scientific Name: Mus musculus   Taxonomy   Common Name: House mouse   Polymer: 2 Scientific Name: Mus musculus   Taxonomy   Common Name: House mouse       Related PDB Entries Hide Identifier Details 1NCW  SAME NATIVE PROTEIN  1ND0  SAME NATIVE PROTEIN COMPLEX WITH TRANSITION STATE ANALOG  1ru9  Crystal Structure of u.v.-irradiated cationic cyclization antibody 4C6 Fab at pH 4.6 with a data set collected in-house.  1rua  Crystal structure of u.v.-irradiated cationic cyclization antibody 4C6 fab at pH 4.6 with a data set collected at SSRL beamline 11-1.  1ruk  Crystal structure of native cationic cyclization antibody 4C6 fab at pH 4.6 with a data set collected at SSRL beamline 9-1  1rul  Crystal Structure of u.v.-irradiated cationic cyclization antibody 4C6 Fab at pH 5.6 with a data set collected at SSRL beamline 11-1.  1rum  Crystal structure of H2O2-soaked cationic cyclization antibody 4C6 fab at pH 8.5 with a data set collected at SSRL beamline 9-1.      Ligand Chemical Component Hide Identifier Formula Name Interactions BEZ Search  Download  C7 H6 O2 BENZOIC ACID   Ligand Explorer GOL Search  Download  C3 H8 O3 GLYCEROL   Ligand Explorer     External Domain Annotations Hide SCOP Classification v1.75: 4 Domains - data from SCOP   CATH Classification v3.4.0: 4 Domains - data from CATH   Pfam Classification: 4 Domains - data from Pfam       Structural Biology Knowledgebase Data Hide     Data in orange boxes are gathered from external resources (when available). Reset Layout

Biological Assembly            View in 3D More Images... Biological assembly 1 assigned by authors and generated by PISA (software) Downloadable viewers: Simple Viewer Protein Workshop Ligand Explorer Kiosk Viewer Other Viewers  KiNG WebMol QuickPDB FirstGlance         MyPDB Personal Annotations Hide     Deposition Summary Hide Authors:   Zhu, X.,  Wentworth Jr., P.,  Wentworth, A.D.,  Eschenmoser, A.,  Lerner, R.A.,  Wilson, I.A. Deposition:   2003-12-11 Release:   2004-03-02 Last Modified (REVDAT):   2011-07-13     Revision History    Hide Mouse over text for details 2011-07-13 Version format compliance 2011-07-13 Non-polymer description     Experimental Details Hide Method:   X-RAY DIFFRACTION Exp. Data:   Structure Factors EDS   Resolution[Å]:   1.40 R-Value: 0.161 (work) R-Free: 0.212 Space Group: P 41 21 2 Unit Cell:   Length [Å] Angles [°] a = 64.20 α = 90.00  b = 64.20 β = 90.00  c = 266.48 γ = 90.00      Molecule of the Month Hide Epidermal Growth Factor Nanobodies Antibodies Hemagglutinin