GELDANAMYCIN BOUND TO THE HSP90 GELDANAMYCIN-BINDING DOMAIN DOI:10.2210/pdb1yet/pdb

1YET   Display Files  close FASTA Sequence PDB File PDB File (Header) mmCIF File mmCIF File (Header) PDBML/XML File PDBML/XML File (Header)   Download Files  close FASTA Sequence PDB File (Text) PDB File (gz) mmCIF File mmCIF File (gz) PDBML/XML File PDBML/XML File (gz) Biological Assembly (gz) (A)   Share this Page  close Facebook Twitter LinkedIn Email Link this Page

Primary Citation       Related Citations in PDB Entry (REMARK 1) Hide     Molecular Description Hide Classification: Chaperone Protein Structure Weight: 26231.64 Molecule: HEAT SHOCK PROTEIN 90 Polymer: 1 Type: protein Length: 228 Chains: A Fragment: RESIDUES 9 - 236 Organism Homo sapiens Gene Names HSP90AA1 HSP90A HSPC1 HSPCA UniProtKB:   Protein Feature View | Search PDB | P07900         Source Hide Polymer: 1 Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli       Ligand Chemical Component Hide Identifier Formula Name Interactions GDM Search  Download  C29 H40 N2 O9 GELDANAMYCIN   Ligand Explorer     External Ligand Annotations Hide Identifier   Binding Affinity (Sequence Identity %) GDM Search  Download  EC50: 35 nM (91) - data from BindingDB   IC50: 20 - 40 nM (91 - 99) - data from BindingDB   Kd: 670 - 1215 nM (91 - 99) - data from BindingDB   N/A in BindingMoad N/A in PDBbind     External Domain Annotations Hide SCOP Classification v1.75: 1 Domain - data from SCOP   CATH Classification v3.4.0: 1 Domain - data from CATH   Pfam Classification: 3 Domains - data from Pfam       Structural Biology Knowledgebase Data Hide     Data in orange boxes are gathered from external resources (when available). Reset Layout

Biological Assembly            View in 3D More Images... Biological assembly 1 assigned by authors Downloadable viewers: Simple Viewer Protein Workshop Ligand Explorer Kiosk Viewer Other Viewers  KiNG WebMol QuickPDB FirstGlance         MyPDB Personal Annotations Hide     Deposition Summary Hide Authors:   Stebbins, C.E.,  Russo, A.A.,  Pavletich, N.P. Deposition:   1997-03-25 Release:   1998-04-22 Last Modified (REVDAT):   2009-02-24     Revision History    Hide Mouse over text for details 2011-07-13 Version format compliance     Experimental Details Hide Method:   X-RAY DIFFRACTION Exp. Data: N/A Resolution[Å]:   1.90 R-Value: 0.193 (obs.) R-Free: n/a Space Group: P 21 Unit Cell:   Length [Å] Angles [°] a = 53.70 α = 90.00  b = 44.30 β = 116.10  c = 54.65 γ = 90.00      Molecule of the Month Hide Hsp90