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CRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA
 
 
DOI:10.2210/pdb1vkx/pdb   NDB ID: PDR033
1VKX
 
Primary Citation
spinning wheel
 
 
  •  
    Move Section Molecular Description Hide
    Classification: Transcription/dna
    Structure Weight: 73235.36
     
    Molecule:DNA (5'-D(*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*C)-3')
    Polymer:1Type:polydeoxyribonucleotideLength:12
    Chains:C
    Other Details:ACTIVE NF-KAPPA-B IS A HETERODIMER OF AN ABOUT 50 KD DNA-BINDING SUBUNIT AND THE WEAK DNA-BINDING SUBUNIT P65
    Molecule:DNA (5'-D(*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*C)-3')
    Polymer:2Type:polydeoxyribonucleotideLength:12
    Chains:D
    Other Details:ACTIVE NF-KAPPA-B IS A HETERODIMER OF AN ABOUT 50 KD DNA-BINDING SUBUNIT AND THE WEAK DNA-BINDING SUBUNIT P65
    Molecule:PROTEIN (NF-KAPPA B P65 SUBUNIT)
    Polymer:3Type:polypeptide(L)Length:273
    Chains:A
    Molecule:PROTEIN (NF-KAPPA B P50 SUBUNIT)
    Polymer:4Type:polypeptide(L)Length:312
    Chains:B
     
     
  •  
    Move Section Source Hide
    Polymer: 1
    Scientific Name: Synthetic construct Go to NCBI Taxonomy entry  
    Polymer: 2
    Scientific Name: Synthetic construct Go to NCBI Taxonomy entry  
    Polymer: 3
    Scientific Name: Mus musculus Go to NCBI Taxonomy entry Common Name: House mouse  
    Polymer: 4
    Scientific Name: Mus musculus Go to NCBI Taxonomy entry Common Name: House mouse  
     
     
  •  
    Move Section Derived Data Hide
     
     
 
 
  •  
    Move Section Deposition Summary Hide
    Authors:   Chen, F.,   Huang, D.B.,   Ghosh, G.

    Deposition:   1997-09-17
    Release:   1998-12-09
    Last Modified (REVDAT):   2009-02-24
     
     
  •  
    Move Section Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Experimental Data:   N/A
    View a histogram of Resolution Resolution[Å]: 2.90
    R-Value: 0.208 (obs.)
    R-Free: 0.320
    Space Group: P 43 21 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 106.61 α = 90.00 
    b = 106.61 β = 90.00 
    c = 206.56 γ = 90.00