1SLO

FIRST STEM LOOP OF THE SL1 RNA FROM CAENORHABDITIS ELEGANS, NMR, MINIMIZED AVERAGE STRUCTURE

Experimental Data Snapshot

  • Method: SOLUTION NMR
  • Conformers Calculated: 16 
  • Conformers Submitted: 1 
  • Selection Criteria: MINIMIZED AVERAGE 

wwPDB Validation   3D Report Full Report


This is version 1.3 of the entry. See complete history. 


Literature

Solution structure of the donor site of a trans-splicing RNA.

Greenbaum, N.L., Radhakrishnan, I., Patel, D.J., Hirsh, D.

(1996) Structure 4: 725-733

  • DOI: https://doi.org/10.1016/s0969-2126(96)00078-0
  • Primary Citation of Related Structures:  
    1SLO, 1SLP

  • PubMed Abstract: 

    RNA splicing is both ubiquitous and essential for the maturation of precursor mRNA molecules in eukaryotes. The process of trans-splicing involves the transfer of a short spliced leader (SL) RNA sequence to a consensus acceptor site on a separate pre-mRNA transcript. In Caenorhabditis elegans, a majority of pre-mRNA transcripts receive the 22-nucleotide SL from the SL1 RNA. Very little is known about the various roles that RNA structures play in the complex conformational rearrangements and reactions involved in premRNA splicing.

    • Organizational Affiliation: 

    Department of Biochemistry and Molecular Biophysics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. greenbau@cuhhca.hhmi.columbia.edu


Macromolecules

Find similar nucleic acids by:  Sequence   |   3D Structure  

Entity ID: 1
MoleculeChains LengthOrganismImage
RNA (5'-R(*UP*UP*AP*CP*CP*CP*AP*AP*GP*UP*UP*UP*GP*AP*GP*GP*UP*AP*A)-3')19Caenorhabditis elegans
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: SOLUTION NMR
  • Conformers Calculated: 16 
  • Conformers Submitted: 1 
  • Selection Criteria: MINIMIZED AVERAGE 

Structure Validation

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Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 1996-12-07
    Type: Initial release
  • Version 1.1: 2008-03-05
    Changes: Version format compliance
  • Version 1.2: 2011-07-13
    Changes: Version format compliance
  • Version 1.3: 2022-03-02
    Changes: Database references, Derived calculations, Other